Improving Your Infectious Disease Screening

ASR Tropical Disease Products

Flavivirus’ are a subset of the family of viral agents capable of causing encephalitis and jaundice1. Most flaviviruses are arboviruses and transmitted to the human population by a bite from infected mosquitoes or ticks.

The Genetic Signatures ASR Flavivirus/Alphavirus Detection Reagents has been designed to provide rapid and accurate detection of 17 species including Pan-flavivirus, Pan-alphavirus and Pan-dengue as detailed below.

The reagents are grouped such that a specific secondary typing assay can be selected and performed once the initial Flavivirus, Alphavirus, Dengue virus identification has occurred using the screening kit.

The reagents also include both an Extraction Control and an Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

Flavivirus/Dengue/Alphavirus detection reagents
Pan-Flavivirus Pan-Dengue 1-4 (DENV) Pan-Alphavirus
Zika Virus (ZIKV) Dengue 1 (DENV 1) Murray Valley Encephalitis Virus (MVEV)
West Nile Virus (WNV) Dengue 2 (DENV 2) Chikungunya virus (CHIKV)
Yellow Fever Virus (YFV) Dengue 3 (DENV 3) Ross River Virus (RRV)
St Louis Encephalitis Virus (SLEV) Dengue 4 (DENV 4) Barmah Forest virus (BFV)
Tick Borne Encephalitis Virus (TBEV)
Japanese Encephalitis Virus (JEV) Eastern equine encephalitis virus (EEEV) Western equine encephalitis viruses (WEEV)
Venezuelan Equine Encephalitis Virus (VEEV) O'nyong'nyong virus (ONNV)

ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

Regulatory

  • Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
  • EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.
  • EasyScreenTM Pathogen Detection Kits are for research use only and are not available for in vitro diagnostic use in America. Genetic Signatures also supplies a range of Analyte Specific Reagents for customers in the USA/North America.
  • Positive controls are not provided for the Flavirus and Alphavirus Reflex Detection Kits.
  • No commercially quantified positive targets are available for MVEV, BFV and ONNV. Therefore, sensitivity performance is not established for these products.

1 Shi, P-Y (editor) (2012). Molecular Virology and Control of Flaviviruses. Caister Academic Press. ISBN 978-1-904455-92-9