ASR Tropical Disease Products
Flavivirus’ are a subset of the family of viral agents capable of causing encephalitis and jaundice1. Most flaviviruses are arboviruses and transmitted to the human population by a bite from infected mosquitoes or ticks.
The Genetic Signatures ASR Flavivirus/Alphavirus Detection Reagents has been designed to provide rapid and accurate detection of 17 species including Pan-flavivirus, Pan-alphavirus and Pan-dengue as detailed below.
The reagents are grouped such that a specific secondary typing assay can be selected and performed once the initial Flavivirus, Alphavirus, Dengue virus identification has occurred using the screening kit.
The reagents also include both an Extraction Control and an Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.
Flavivirus Dengue Alphavirus Detection Reagents
| AFV001-4 | Pan-Flavivirus Primers and Probe |
| AFV002-3 | Pan-Dengue 1-4 (DENV) Primers and Probe |
| AFV003-1 | Dengue 1 (DENV 1) Primers and Probe |
| AFV004-3 | Dengue 2 (DENV 2) Primers and Probe |
| AFV005-4 | Dengue 3 (DENV 3) Primers and Probe |
| AFV006-1 | Dengue 4 (DENV 4) Primers and Probe |
| AFV007-1 | Zika Virus (ZIKV) Primers and Probe |
| AFV008-1 | West Nile Virus (WNV) Primers and Probe |
| AFV009-4 | Yellow Fever Virus (YFV) Primers and Probe |
| AFV010-1 | St Louis Encephalitis Virus (SLEV) Primers and Probe |
| AFV011-1 | Tick Borne Encephalitis Virus (TBEV) Primers and Probe |
| AFV012-4 | Japanese Encephalitis Virus (JEV) Primers and Probe |
| AAV001-1 | Pan-Alphavirus Primers and Probe |
| AAV002-3 | Murray Valley Encephalitis Virus (MVEV) Primers and Probe |
| AAV003-1 | Chikungunya virus (CHIKV) Primers and Probe |
| AAV004-3 | Ross River Virus (RRV) Primers and Probe |
| AAV005-4 | Barmah Forest virus (BFV) Primers and Probe |
| AAV006-1 | Eastern equine encephalitis virus (EEEV) Primers and Probe |
| AAV007-3 | Western equine encephalitis viruses (WEEV) Primers and Probe |
| AAV008-1 | Venezuelan Equine Encephalitis Virus (VEEV) Primers and Probe |
| AAV009-1 | O’nyong’nyong virus (ONNV) Primers and Probe |
ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.
Regulatory
- Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
- EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.
- EasyScreenTM Pathogen Detection Kits are for research use only and are not available for in vitro diagnostic use in America. Genetic Signatures also supplies a range of Analyte Specific Reagents for customers in the USA/North America.
- Positive controls are not provided for the Flavirus and Alphavirus Reflex Detection Kits.
- No commercially quantified positive targets are available for MVEV, BFV and ONNV. Therefore, sensitivity performance is not established for these products.
