Meningitis Detection
Meningitis is a central nervous system (CNS) infection that can have serious clinical manifestations. Viral, Bacterial and Fungal meningitis are serious infections that require rapid diagnosis for the support of high-risk patients.
Molecular detection methods offer the advantages of speed, and ability to screen for a larger number of pathogens than conventional methods.
The Genetic Signatures ASR Meningitis Detection Reagents have been designed to provide rapid and accurate detection of multiple viral, bacterial and fungal meningitis.
Viral meningitis can be caused by a number of viruses, including Herpesviruses, Human Parechovirus and Enterovirus. It is a common infection that causes “flu-like” symptoms, and is usually self- limiting, hence it does not require specific treatment in most cases. Rapid diagnosis is important however, to rule out a more serious bacterial meningitis infection, and to provide support to high-risk patients.
Molecular detection methods offer the advantages of speed, and ability to screen for a larger number of pathogens than conventional methods.
Viral Meningitis Targets
| AVM001-4 | Enterovirus Primers and Probe |
| AVM002-3 | Human parechovirus (HPeV) Primers and Probe |
| AVM003-1 | Herpes simplex virus 1 (HSV1) Primers and Probe |
| AVM004-3 | Herpes simplex virus 2 (HSV2) Primers and Probe |
| AVM005-4 | Varicella zoster virus (VZV) Primers and Probe |
| AVM006-3 | Epstein-Barr virus (EBV) Primers and Probe |
| AVM007-1 | Cytomegalovirus (CMV) Primers and Probe |
| AVM008-4 | Human herpesvirus 6 (HHV6) Primers and Probe |
ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.
The Product Code suffix indicates the detection channel for each real-time PCR probe.
Regulatory
- Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
- EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.
Bacterial meningitis develops quickly and requires immediate medical attention, as it can be fatal without prompt treatment. Several types of bacteria can cause meningitis.
The Genetic Signatures' Bacterial Meningitis ASRs have been designed to detect the most common bacterial meningitis-causing infections.
Bacterial Meningitis Targets
| ABM001-1 | Haemophilus influenzae Primers and Probe |
| ABM002-3 | Mycoplasma pneumoniae Primers and Probe |
| ABM003-4 | Streptococcus agalactiae Primers and Probe |
| ABM004-3 | Escherichia coli Primers and Probe |
| ABM005-1 | Streptococcus pneumoniae Primers and Probe |
| ABM006-4 | Neisseria meningitides (Meningococcus) Primers and Probe |
| ABM007-1 | Listeria monocytogenes Primers and Probe |
| ABM008-3 | Mycobacterium tuberculosis Primers and Probe |
ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.
The Product Code suffix indicates the detection channel for each real-time PCR probe.
Regulatory
- Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
- EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.
Fungal meningitis is rare and can develop after a fungus spreads from somewhere else in the body to the brain or spinal cord.
The Genetic Signatures Fungal Meningitis ASRs has been designed to detect a common fungal causing pathogen.
Fungal Meningitis Targets
| AFM001-4 | Cryptococcus neoformans (Cryptococcus) Primers and Probe |
ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.
The Product Code suffix indicates the detection channel for each real-time PCR probe.
Regulatory
- Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
- EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.
Compatible specimens include CSF, plasma, saliva and swabs.
ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.
Regulatory
- Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
- EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.
- EasyScreenTM Pathogen Detection Kits are for research use only and are not available for in vitro diagnostic use in America. Genetic Signatures also supplies a range of Analyte Specific Reagents for customers in the USA/North America.
