Improving Your Infectious Disease Screening

Meningitis Detection

Meningitis is a central nervous system (CNS) infection that can have serious clinical manifestations. Viral, Bacterial and Fungal meningitis are serious infections that require rapid diagnosis for the support of high-risk patients.

Molecular detection methods offer the advantages of speed, and ability to screen for a larger number of pathogens than conventional methods.

The Genetic Signatures ASR Meningitis Detection Reagents have been designed to provide rapid and accurate detection of multiple viral, bacterial and fungal meningitis.

Viral Meningitis Detection Reagents

Viral meningitis can be caused by a number of viruses, including Herpesviruses, Human Parechovirus and Enterovirus.  It is a common infection that causes “flu-like” symptoms, and is usually self- limiting, hence it does not require specific treatment in most cases. Rapid diagnosis is important however, to rule out a more serious bacterial meningitis infection, and to provide support to high-risk patients.

Molecular detection methods offer the advantages of speed, and ability to screen for a larger number of pathogens than conventional methods.

 

Viral Meningitis Targets

AVM001-4 Enterovirus Primers and Probe
AVM002-3 Human parechovirus (HPeV) Primers and Probe
AVM003-1 Herpes simplex virus 1 (HSV1) Primers and Probe
AVM004-3 Herpes simplex virus 2 (HSV2) Primers and Probe
AVM005-4 Varicella zoster virus (VZV) Primers and Probe
AVM006-3 Epstein-Barr virus (EBV) Primers and Probe
AVM007-1 Cytomegalovirus (CMV) Primers and Probe
AVM008-4 Human herpesvirus 6 (HHV6) Primers and Probe

ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

The Product Code suffix indicates the detection channel for each real-time PCR probe.

 

Regulatory

  • Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
  • EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.

Bacterial Meningitis Detection Reagents

Bacterial meningitis develops quickly and requires immediate medical attention, as it can be fatal without prompt treatment. Several types of bacteria can cause meningitis.

The Genetic Signatures' Bacterial Meningitis ASRs have been designed to detect the most common bacterial meningitis-causing infections.

 

Bacterial Meningitis Targets

ABM001-1 Haemophilus influenzae Primers and Probe
ABM002-3 Mycoplasma pneumoniae Primers and Probe
ABM003-4 Streptococcus agalactiae Primers and Probe
ABM004-3 Escherichia coli Primers and Probe
ABM005-1 Streptococcus pneumoniae Primers and Probe
ABM006-4 Neisseria meningitides (Meningococcus) Primers and Probe
ABM007-1 Listeria monocytogenes Primers and Probe
ABM008-3 Mycobacterium tuberculosis Primers and Probe

ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

The Product Code suffix indicates the detection channel for each real-time PCR probe.

 

Regulatory

  • Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
  • EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.

Fungal Meningitis Detection Reagents

Fungal meningitis is rare and can develop after a fungus spreads from somewhere else in the body to the brain or spinal cord.

The Genetic Signatures Fungal Meningitis ASRs has been designed to detect a common fungal causing pathogen.

 

Fungal Meningitis Targets

AFM001-4 Cryptococcus neoformans (Cryptococcus) Primers and Probe

ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

The Product Code suffix indicates the detection channel for each real-time PCR probe.

 

Regulatory

  • Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
  • EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.

Compatible specimens include CSF, plasma, saliva and swabs.

ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

Regulatory

  • Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
  • EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.
  • EasyScreenTM Pathogen Detection Kits are for research use only and are not available for in vitro diagnostic use in America. Genetic Signatures also supplies a range of Analyte Specific Reagents for customers in the USA/North America.