Improving Your Infectious Disease Screening

Extended Spectrum Beta-Lactamase (ESBL) & Carbapenemase Producing Organisms (CPO) Antimicrobial importance

Our ASR range of Antimicrobial resistance products are in-vitro nucleic acid amplification assays for the qualitative detection of ESBL and CPO pathogens.

ESBL and MCR Detection Reagents

Beta-lactam antibiotics are the most commonly used antibiotics worldwide for the treatment of bacterial infections. Extended Spectrum Beta-Lactamase (ESBL) producing organisms hydrolyze cephalosporins, penicillins, and aztreonam, rendering them ineffective for the treatment of infected patients. This makes accurate and timely detection of ESBL and Carbapenemase Producing Organisms (CPO) important as it will have a significant impact on patient management.

ESBL and MCR targets
Pan-TEM Pan-CMY
Pan-CTX-M Pan-SHV
MCR-1 Pan-DHA

ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

Regulatory

  • Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
  • EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.

CPO Detection Reagents

Carbapenem based antibiotics have become the first line choice in the treatment of ESBL infections. Of significant global concern therefor is the emergence of carbapenem resistant (CPO) bacteria in healthcare settings, as standard treatments may be rendered ineffective.

Carbapenem resistant targets (CPO)
NDM KPC Vim2
IMP Oxa-23 like Oxa-51 like
GES IMI SME

ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

The Product Code suffix indicates the detection channel for each real-time PCR probe.

 

Regulatory

  • Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
  • EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.

ASRs also include an Extraction and Internal Positive Control for each sample to ensure the quality of the extracted DNA and to detect the presence of any inhibitors, respectively.

Regulatory

  • Analyte Specific Reagents (ASRs). Analytical and performance characteristics are not characterized.
  • EasyScreenTM Sample Processing Kits are FDA-listed clinical concentrators.
  • EasyScreenTM Pathogen Detection Kits are for research use only and are not available for in vitro diagnostic use in America. Genetic Signatures also supplies a range of Analyte Specific Reagents for customers in the USA/North America.