Intellectual Property

Genetic Signatures Ltd has a broad patent portfolio covering its core technologies that include a number of patent families.
A summary of our patent portfolio can be found here

These inventions can be broadly grouped into the following categories:

Current Technologies

• Simplification of Genomes for Microbial Detection (3base™)
  Treating naturally occurring nucleic acids with bisulphite and using the resultant modified nucleic acids to detect pathogens and disease.
• Methylation Detection Kits (MethylEasy™)
  Products to enable R&D organisations to detect methylation patterns in DNA.

Emerging Technologies

• Methylation Detection
  A variety of methods and techniques to explore these phenomena in nucleic acids by the specific amplification of methylated sequences.
• Isothermal Amplification
  A method for amplification and detection of nucleic acids at a fixed temperature.
• Engineered enzymes for enhanced PCR
  A novel enzyme has been engineered, in collaboration with the LMB in Cambridge UK, to improve the efficiency and speed of PCR amplification of bisulphite treated nucleic acids.
• Improving cervical cancer diagnosis
  A method combining the detection of HPV with the methylation status of the infected genome to improve cancer diagnosis and reduce needless surgical intervention.

To discuss licensing Genetic Signatures' technology, contact licensing@geneticsignatures.com.