Category Archives: Latest News

Hear about Genetic Signatures EasyScreen™ Kits at the upcoming 2017 NRL Workshop on Molecular Diagnostics

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Genetic Signatures EasyScreen™ Pathogen Detection Kits will be featured in an oral presentation at the upcoming National Reference Laboratory (NRL) Workshop on Molecular Diagnostics on the 16-17th October 2017 Hobart, Australia.

The presentation entitled “A 3baseTM Real-Time Multiplex-PCR for the detection of Extended- Spectrum β -Lactamases (ESBL) and Carbapenemase- Producing Organisms (CPO) will be given by our talented Product Development Scientist Mr. Dilshan Abeysekera.

The NRL Molecular Workshop is a forum for scientists, regulators, test kit manufacturers and clinicians to unite and discuss current issues and new technologies occurring in the world of molecular pathology for infectious diseases. The aim of this workshop is to focus specifically on molecular techniques involved in detecting infectious pathogens.

 Visit the conference website for more information: NRL Molecular Diagnostic Workshop


About ESBL and CPO: ESBLs are enzymes that mediate resistance to extended-spectrum (third generation) cephalosporins and monobactams but do not affect cephamycins or carbapenems. The presence of an ESBL-producing organism in a clinical infection can result in treatment failure if one of the above classes of drugs is used. ESBLs can be difficult to detect because they have different levels of activity against various cephalosporins. Thus, the choice of which antimicrobial agents to test is critical. 1

 CPO or CRE, which stands for carbapenem-resistant Enterobacteriaceae or organisms, are a family of germs that are difficult to treat because they have high levels of resistance to antibiotics. Klebsiella species and Escherichia coli (E. coli) are examples of Enterobacteriaceae, a normal part of the human gut bacteria, that can become carbapenem-resistant. Types of CRE are sometimes known as KPC (Klebsiella pneumoniae carbapenemase) and NDM (New Delhi Metallo-beta-lactamase). KPC and NDM are enzymes that break down carbapenems and make them ineffective. Both of these enzymes, as well as the enzyme VIM (Verona Integron-Mediated Metallo-β-lactamase) have also been reported in Pseudomonas.

Healthy people usually do not get CRE infections – they usually happen to patients in hospitals, nursing homes, and other healthcare settings. Patients whose care requires devices like ventilators (breathing machines), urinary (bladder) catheters, or intravenous (vein) catheters, and patients who are taking long courses of certain antibiotics are most at risk for CRE infections.

Some CRE bacteria have become resistant to most available antibiotics. Infections with these germs are very difficult to treat, and can be deadly—one report cites they can contribute to death in up to 50% of patients who become infected.2

About the EasyScreen™ Antibiotic Resistance Detection Kit: The EasyScreen™ Antibiotic Resistance Detection Kit detects the most common resistant markers. ESBL and CPO targets that are detected are β –Lactamases TEM, SHV, CTX-M, CMY, DHA,OXA-48 like , OXA- 23 like, OXA-51 like, GES, MCR-1,IMI,SME, , New Delhi Metallo- β –Lactamases (NDM), Klebsiella pneumoniae carbapenemase (KPC), Metallo- β –Lactamases VIM, Metallo- β –Lactamases IMP.

References:
1. https://www.cdc.gov/hai/settings/lab/lab_esbl.html
2. https://www.cdc.gov/hai/organisms/cre/index.html

Genetic Signatures to exhibit and present at the 10th European Meeting on Molecular Diagnostics (EMMD), Noordwijk, Netherlands

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Genetic Signatures are proud to announce the exhibition and presentation at the 10th European Meeting on Molecular Diagnostics (EMMD) on the 11-13th October 2017 Noordwijk, Netherlands.

This biannual event with multiple keynote speakers provides a unique opportunity to showcase applications in novel molecular technologies as well as highlight the key aspects required in Molecular Diagnostics.

We are pleased to announce that Genetic Signatures Director, US Technical Operations Dr. Richard Smith will be presenting.

Session 9: New Diagnostics Technologies

Friday October 13th, 2017 at 15:25 – 15:40 (CEST)

Rapid, Sensitive and Automated Detection of Pathogenic Targets with the Multiplexed EasyScreen™ 3base™ Assays

Please visit Genetic Signatures at Booth 14 to learn more about our novel 3baseTM technology and applications with our EasyScreenTM Detection Kits.

Visit the conference website for more information: EMMD


 

About EMMD: This is the 10th European Meeting on Molecular Diagnostics (EMMD), devoted to all aspects of molecular diagnostics in human disease and pathology. The EMMD is organised every two years in the Netherlands. These meetings are a continuation of the former Benelux- and European meetings on PCR diagnostics. However, the scope of the meeting has expanded to include other amplification techniques, general probe technology and applications in a wide diversity of laboratory disciplines such as Clinical Microbiology, Virology, Pathology, Clinical Chemistry, Clinical Genetics, Pharmacogenetics, Hematology, and Oncology.

The emphasis of this multi-disciplinary meeting is on novel molecular technologies and innovative applications in the diagnosis, monitoring, and screening of human diseases. Presentations will consist of invited-lectures by internationally renowned experts in combination with selected abstract presentations. Poster sessions and industrial exhibits will be an integrated part of the meeting.

 

Genetic Signatures to present at ASM Tri-State Scientific Meeting & Parasitology Masterclass 22-25 September, Darwin, Australia.

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Genetic Signatures have been invited to present at the 2017 ASM Tri-State Scientific Meeting & Parasitology Masterclass 22-25 September, Darwin, Australia.

Genetic Signatures Chief Scientific Officer (CSO) Dr. Doug Millar will be presenting the results on the development of a 3baseTM Flavivirus and Alphavirus EasyScreenTM Detection assay. The test allows for the detection of 17 of the most common flavivirus and alphavirus infections in the world, including dengue, West Nile virus, Zika, yellow fever virus, and chikungunya.

We invite you to hear Dr. Millar’s presentation at Tri-State Scientific Meeting & Parasitology Masterclass: Monday 25th September 2017 at 11:30 am (EST)

Click here to visit the ASM website


About ASM Tri-State Scientific Meeting & Parasitology Masterclass 2017: Tri-State meetings have been initiated and supported by ASM branches in SA, WA and NT for over 25 years. The aim of this meeting is to bring delegates together in an intimate and unique environment. Expect a varied and engaging scientific program presented by some of Australia’s top microbiologists.

The Parasitology Masterclass began with its inaugural meeting in Tasmania in 2009, this is the 6th Parasitology Masterclass, it aims to again provide an excellent blend of wet workshops, classroom teaching, and formal presentations.

Genetic Signatures to Exhibit and Present at the annual Australian Society of Microbiology (ASM) meeting, 2-5 July, Hobart, Tasmania

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Genetic Signatures are proud to exhibit at the Australian Society for Microbiology Annual Scientific Meeting (ASM) 2017 in Hobart, Tasmania on 2-5 July 2017.

Genetic Signatures has also been selected to present 4 oral papers at ASM 2017 Tasmania, in the following sessions:

  • Monday 3rd July, 2017 10:30-12:00pm EST
    Session: Laboratory Processes and Automation
    “Clinical evaluation of the 3base™ EasyScreenTM Enteric Viral Detection Kit EV002”
  • Monday 3rd July, 2017 15.30-17:00pm EST
    Session: Virus-host interactions
    “A novel 3base™ assay for the rapid detection of flavivirus/alphavirus in clinical samples
  • Tuesday 4th July, 2017 10:30-12:00pm EST
    Session: New Clinical Microbiology Diagnostics
    “A 3base™ Real-Time Multiplex-PCR method for the detection of Extended-Spectrum β-Lactamases (ESBL) and Carbapenemase-Producing Organisms (CPO)”
  • Tuesday 4rd July, 2017 15:30-17:00pm EST
    Session: STIs and Diagnostics
    “Rapid, Sensitive and Automated Detection of 12 Bacterial and Viral Causes of Sexually Transmitted Infections using the 3base™ EasyScreenTM Sexually Transmitted/Genital Detection Kit”

You are invited to visit Genetic Signatures at Booth no. 17 and to attend the oral presentations at ASM 2017 Tasmania.

Click here to visit the ASM 2017 Tasmania website

Planetary Health ASM 2017 Hobart


About ASM 2017 Tasmania: The Australian Society for Microbiology Annual Scientific Meeting (ASM) was formed in 1959 as a learned society devoted to furthering the science of microbiology. The ASM became an incorporated professional society in 1976.

With the theme of Planetary Health, the scientific program emphasizes the interdependent nature of life on Earth and how this relates to the health of mankind. An exciting new discipline, Planetary Health encompasses broad microbial systems that impact disease and epidemiology, climate change, food production and many broad natural systems. The annual meeting represents an opportunity to showcase products and technology to over 500 delegates from both diagnostic and research backgrounds.

Genetic Signatures Exhibiting at ASM Microbe 2017 in New Orleans, Louisiana, United States, 1-5 June 2017.

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Genetic Signatures are pleased to be exhibiting at ASM Microbe 2017 in New Orleans, Louisiana, United States, 1-5 June 2017.

The ASM Microbe conference showcases the best microbial sciences in the world and provides a one-of-a-kind forum to explore the complete spectrum of microbiology from basic science to translation and application.

You are invited to visit Genetic Signatures at Booth no. 1304 at ASM Microbe 2017.

Click here to visit the ASM Microbe website 

ASM Microbe 2017


About ASM Microbe: ASM Microbe 2017 is the largest gathering of microbiologists in the world and the only meeting in the field that explores the full scope of microbiology – from basic science to translational and clinical application. By integrating ASM’s two most popular events, General Meeting and ICAAC, ASM Microbe 2017 provides unparalleled learning and networking opportunities that you cannot find anywhere else.

Genetic Signatures exhibiting at the 33rd ASM Clinical Virology Symposium (CVS) Savannah, Georgia, United States, 07-10 May 2017.

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Genetic Signatures will be exhibiting at the 33rd ASM Clinical Virology Symposium (CVS) Savannah, Georgia, United States, 07-10 May 2017.

Presented by ASM- The Clinical Virology Symposium is a 3-day event highlighting the relationship between rapid viral diagnosis, clinical course of viral infections and preventive and therapeutic modalities for viral infections being the theme of this premier meeting. Discussion of timely topics by renowned scientists assures that this symposium will be informative and engaging, while newly acquired information about clinically relevant viral infections will be useful to practicing physicians who can apply this knowledge in a clinical setting.

Visit Genetic Signatures at Booth #435 at CVS 2017 for more information.

Click here to visit the ASM website for more information on ASM Clinical Virology Symposium 2017


 About ASM Clinical Virology Symposium: ASM Clinical Virology Symposium is led by biomedical scientists engaged in research as well as primary care physicians and laboratory professions involved with patient care. This international symposium will provide an unmatched forum for the meaningful exchange of ideas dealing with viral infections.

Genetic Signatures Featured in Latest GenomeWeb Article

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GenomeWeb, the largest online newsroom focused on advanced molecular research tools, has featured Genetic Signatures and 3base™ technology, in an article about the company’s continued global market rollout of their existing and new suite of products. The new 3base™ multiplex PCR tests include an assay for detecting sexually transmitted infections and another that tests for all flaviviruses and alphaviruses. These assays complement Genetic Signatures’ tests already available which include assays for enteric and respiratory infections.  The GenomeWeb article highlighted Genetic Signatures’ recent clinical trial of their new EasyScreenTM Flavivirus/Alphavirus Detection kit, which was presented at the infectious diseases conference, ECCMID, in April 2017 (Vienna, Austria).  The article also discussed the ongoing global expansion strategy including the progress of regulatory approval in Australia and a CE-IVD marking of a number of products in the coming months.


 

Read the full article here