Genetic Signatures Ltd has a broad patent portfolio covering its core technologies that includes a number of patent families.
A summary of our patent portfolio can be found here
These inventions can be broadly grouped into the following categories:
- Simplification of Genomes for Microbial Detection (3base™)
Treating naturally occurring nucleic acids with bisulphite and using the resultant modified nucleic acids to detect pathogens and disease.
- Methylation Detection Kits (MethylEasy™)
Products to enable R&D organisations to detect methylation patterns in DNA.
- Methylation Detection
A variety of methods and techniques to explore these phenomena in nucleic acids by the specific amplification of methylated sequences.
- Isothermal Amplification
A method for amplification and detection of nucleic acids at a fixed temperature.
- Engineered enzymes for enhanced PCR
A novel enzyme has been engineered, in collaboration with the LMB in Cambridge UK, to improve the efficiency and speed of PCR amplification of bisulphite treated nucleic acids.
- Improving cervical cancer diagnosis
A method combining the detection of HPV with the methylation status of the infected genome to improve cancer diagnosis and reduce needless surgical intervention.
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